Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Ribociclib plus Endocrine Therapy in Early Breast Cancer.

Slamon, Dennis; Lipatov, Oleg; Nowecki, Zbigniew; McAndrew, Nicholas; Kukielka-Budny, Bozena; Stroyakovskiy, Daniil; Yardley, Denise A; Huang, Chiun-Sheng; Fasching, Peter A; Crown, John; Bardia, Aditya; Chia, Stephen; Im, Seock-Ah; Ruiz-Borrego, Manuel; Loi, Sherene; Xu, Binghe; Hurvitz, Sara; Barrios, Carlos; Untch, Michael; Moroose, Rebecca; Visco, Frances; Afenjar, Karen; Fresco, Rodrigo; Severin, Irene; Ji, Yan; Ghaznawi, Farhat; Li, Zheng; Zarate, Juan P; Chakravartty, Arunava; Taran, Tetiana; Hortobagyi, Gabriel.

N Engl J Med ; 390(12): 1080-1091, 2024 Mar 21.

Artículo en Inglés | MEDLINE | ID: mdl-38507751

2.

Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo.

Ding, Xiaokai; Sharko, Amanda C; McDermott, Martina S J; Schools, Gary P; Chumanevich, Alexander; Ji, Hao; Li, Jing; Zhang, Li; Mack, Zachary T; Sikirzhytski, Vitali; Shtutman, Michael; Ivers, Laura; O'Donovan, Norma; Crown, John; Gyorffy, Balázs; Chen, Mengqian; Roninson, Igor B; Broude, Eugenia V.

Proc Natl Acad Sci U S A ; 119(32): e2201073119, 2022 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-35914167

3.

Carcinoma of unknown primary (CUP): an update for histopathologists.

Beauchamp, Katie; Moran, Bruce; O'Brien, Timothy; Brennan, Donal; Crown, John; Sheahan, Kieran; Cotter, Maura Bríd.

Cancer Metastasis Rev ; 42(4): 1189-1200, 2023 12.

Artículo en Inglés | MEDLINE | ID: mdl-37394540

4.

Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study.

Miceli, Rosalba; Eriksson, Hanna; Lo Russo, Giuseppe; Alfieri, Salvatore; Moksnes Bjaanæs, Maria; Pietrantonio, Filippo; De Cecco, Loris; Prelaj, Arsela; Proto, Claudia; Franzén, Johan; McDonnell, Deirdre; Berenguer Pina, José Javier; Beninato, Teresa; Mazzeo, Laura; Giannatempo, Patrizia; Verzoni, Elena; Crown, John; Helland, Åslaug; Eustace, Alexander.

Acta Oncol ; 63: 213-219, 2024 Apr 21.

Artículo en Inglés | MEDLINE | ID: mdl-38647024

5.

Immune checkpoint inhibitors: Key trials and an emerging role in breast cancer.

Gaynor, Nicola; Crown, John; Collins, Denis M.

Semin Cancer Biol ; 79: 44-57, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-32623044

6.

Targeting p53 for the treatment of cancer.

Duffy, Michael J; Synnott, Naoise C; O'Grady, Shane; Crown, John.

Semin Cancer Biol ; 79: 58-67, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-32741700

7.

Circulating tumor DNA (ctDNA): can it be used as a pan-cancer early detection test?

Duffy, Michael J; Crown, John.

Crit Rev Clin Lab Sci ; : 1-13, 2023 Nov 07.

Artículo en Inglés | MEDLINE | ID: mdl-37936529

8.

Alterations in immune cell phenotype and cytotoxic capacity in HER2+ breast cancer patients receiving HER2-targeted neo-adjuvant therapy.

Gaynor, Nicola; Blanco, Alfonso; Madden, Stephen F; Moran, Barry; Fletcher, Jean M; Kaukonen, Damien; Ramírez, Javier Sánchez; Eustace, Alex J; McDermott, Martina S J; Canonici, Alexandra; Toomey, Sinead; Teiserskiene, Ausra; Hennessy, Bryan T; O'Donovan, Norma; Crown, John; Collins, Denis M.

Br J Cancer ; 129(6): 1022-1031, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37507543

9.

Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells.

Tang, Minhong; Crown, John; Duffy, Michael J.

Invest New Drugs ; 41(4): 541-550, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37233863

10.

Vitamin D Supplementation: Does It Have a Preventative or Therapeutic Role in Cancer?

Duffy, Michael J; Mullooly, Maeve; Bennett, Kathleen; Crown, John.

Nutr Cancer ; 75(2): 450-460, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-36495143

11.

Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer.

von Minckwitz, Gunter; Huang, Chiun-Sheng; Mano, Max S; Loibl, Sibylle; Mamounas, Eleftherios P; Untch, Michael; Wolmark, Norman; Rastogi, Priya; Schneeweiss, Andreas; Redondo, Andres; Fischer, Hans H; Jacot, William; Conlin, Alison K; Arce-Salinas, Claudia; Wapnir, Irene L; Jackisch, Christian; DiGiovanna, Michael P; Fasching, Peter A; Crown, John P; Wülfing, Pia; Shao, Zhimin; Rota Caremoli, Elena; Wu, Haiyan; Lam, Lisa H; Tesarowski, David; Smitt, Melanie; Douthwaite, Hannah; Singel, Stina M; Geyer, Charles E.

N Engl J Med ; 380(7): 617-628, 2019 02 14.

Artículo en Inglés | MEDLINE | ID: mdl-30516102

12.

MYC as a therapeutic target for the treatment of triple-negative breast cancer: preclinical investigations with the novel MYC inhibitor, MYCi975.

Tang, Minhong; O'Grady, Shane; Crown, John; Duffy, Michael J.

Breast Cancer Res Treat ; 195(2): 105-115, 2022 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-35908121

13.

Circulating Tumor DNA as a Biomarker for Monitoring Patients with Solid Cancers: Comparison with Standard Protein Biomarkers.

Duffy, Michael J; Crown, John.

Clin Chem ; 68(11): 1381-1390, 2022 11 03.

Artículo en Inglés | MEDLINE | ID: mdl-35962648

14.

Analytical Validation of a Novel 6-Gene Signature for Prediction of Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative, Early-Stage Breast Cancer.

Loughman, Tony; Barron, Stephen; Wang, Chan-Ju Angel; Dynoodt, Peter; Fender, Bozena; Lopez-Ruiz, Cesar; Stapleton, Sharon; Fabre, Aurelie; Quinn, Cecily; Nodin, Bjorn; Jirström, Karin; Razmara, Fatemeh; O'Grady, Anthony; Baird, Anne-Marie; Gray, Steven G; Freixo, Ana; Moelans, Cathy B; van Diest, Paul J; Duffy, Michael J; O'Leary, Desmond; Crown, John; Bracken, Adrian P; Gallagher, William M.

Clin Chem ; 68(6): 837-847, 2022 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-35312747

15.

Endometrial Mesonephric-like Adenocarcinoma Presenting as an Ocular Lesion: A Case Report.

Al Nabhani, Safia; Doyle, Aoife; Kennedy, Susan; McVey, Ruaidhri; Crown, John; Gibbons, David.

Int J Gynecol Pathol ; 41(2): 161-167, 2022 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-33935158

16.

A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer.

Schmid, Peter; Sablin, Marie-Paule; Bergh, Jonas; Im, Seock-Ah; Lu, Yen-Shen; Martínez, Noelia; Neven, Patrick; Lee, Keun Seok; Morales, Serafín; Pérez-Fidalgo, J Alejandro; Adamson, Douglas; Gonçalves, Anthony; Prat, Aleix; Jerusalem, Guy; Schlieker, Laura; Espadero, Rosa-Maria; Bogenrieder, Thomas; Huang, Dennis Chin-Lun; Crown, John; Cortés, Javier.

Breast Cancer Res ; 23(1): 8, 2021 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-33451345

17.

Drugging "undruggable" genes for cancer treatment: Are we making progress?

Duffy, Michael J; Crown, John.

Int J Cancer ; 148(1): 8-17, 2021 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-32638380

18.

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors.

Conlon, Neil T; Kooijman, Jeffrey J; van Gerwen, Suzanne J C; Mulder, Winfried R; Zaman, Guido J R; Diala, Irmina; Eli, Lisa D; Lalani, Alshad S; Crown, John; Collins, Denis M.

Br J Cancer ; 124(7): 1249-1259, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-33473169

19.

Pregnancy-associated breast cancer: evaluating maternal and foetal outcomes. A national study.

Prior, Lisa; O'Dwyer, Richard; Farooq, Abdul Rehman; Greally, Megan; Ward, Cian; O'Leary, Connor; Aslam, Razia; Darwish, Waseem; Ahmed, Nada; Othman, Elly Che; Watson, Geoffrey; Kelly, Deirdre; Gleeson, Jack; Kiely, Lisa; Hassan, Anees; Walsh, Elaine M; O'Reilly, David; Jones, Alfred; Featherstone, Hannah; Lim, Marvin; Murray, Hazel; Hennessy, Bryan T; Smyth, Lillian M; Leonard, Gregory; Grogan, Liam; Breathnach, Oscar; Calvert, Paula; Horgan, Anne M; Coate, Linda; Jordan, Emmet J; O'Mahony, Deirdre; Gupta, Rajnish; Keane, Maccon M; Westrup, Jennifer; Duffy, Karen; O'Connor, Miriam; Morris, Patrick G; Kennedy, M John; O'Reilly, Seamus; McCaffrey, John; Kelly, Catherine M; Carney, Desmond; Gullo, Giuseppe; Crown, John; Higgins, Michaela J; Walsh, Paul M; Walshe, Janice M.

Breast Cancer Res Treat ; 189(1): 269-283, 2021 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-34125341

20.

The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells.

AlSultan, Dalal; Kavanagh, Emma; O'Grady, Shane; Eustace, Alex J; Castell, Alina; Larsson, Lars-Gunnar; Crown, John; Madden, Stephen F; Duffy, Michael J.

Invest New Drugs ; 39(2): 587-594, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33052557

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Ribociclib plus Endocrine Therapy in Early Breast Cancer.

Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo.

Carcinoma of unknown primary (CUP): an update for histopathologists.

Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study.

Immune checkpoint inhibitors: Key trials and an emerging role in breast cancer.

Targeting p53 for the treatment of cancer.

Circulating tumor DNA (ctDNA): can it be used as a pan-cancer early detection test?

Alterations in immune cell phenotype and cytotoxic capacity in HER2+ breast cancer patients receiving HER2-targeted neo-adjuvant therapy.

Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells.

Vitamin D Supplementation: Does It Have a Preventative or Therapeutic Role in Cancer?

Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer.

MYC as a therapeutic target for the treatment of triple-negative breast cancer: preclinical investigations with the novel MYC inhibitor, MYCi975.

Circulating Tumor DNA as a Biomarker for Monitoring Patients with Solid Cancers: Comparison with Standard Protein Biomarkers.

Analytical Validation of a Novel 6-Gene Signature for Prediction of Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative, Early-Stage Breast Cancer.

Endometrial Mesonephric-like Adenocarcinoma Presenting as an Ocular Lesion: A Case Report.

A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer.

Drugging "undruggable" genes for cancer treatment: Are we making progress?

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors.

Pregnancy-associated breast cancer: evaluating maternal and foetal outcomes. A national study.

The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells.